WHITE LESION (LEUKOPLAKIA)
- Lesions that appear as white patches in oral cavity
- White lesionsare normally seen in the oral cavity and are often found as an incidental finding on routine examination
- Oral white lesionscan be caused by a thickened keratotic layer or an accumulation of non-keratotic material.
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- Leukoplakia is a condition in which thick, white or grayish patches form usually inside your mouth.
- Mild leukoplakia is usually harmless and often goes away on its own. (On Removal of cause)
- More serious cases may be linked to oral cancer and must be treated promptly.
- Regular dental care can help prevent recurrences.
SYMPTOMS:
- Leukoplakia occurs on parts of the body that have mucosal tissue, such as the mouth.
- The condition is marked by unusual-looking patches inside your mouth.
- Redness may be a sign of cancer. See your doctor right away if you have patches with red spots.
- Leukoplakia can occur on your gums, the inside of your cheeks, under or on your tongue, and even on your lips. The patches may take several weeks to develop. They’re rarely
CAUSES:
- The exact cause of leukoplakia is unknown.
- It’s primarily linked to tobacco use. Smoking is the most common cause. But chewing tobacco can also cause leukoplakia.
Other causes include:
- injury to the inside of your cheek, such as from biting
- rough, uneven teeth
- dentures, especially if improperly fitted
- inflammatory conditions of the body
- long-term alcohol use
HAIRY LEUKOPLAKIA:
- The Epstein-Barr virus (EBV) is the main cause of hairy leukoplakia. Once you get this virus, it remains in your body permanently. EBV is usually dormant.
- However, it can cause hairy leukoplakia patches to develop at any time. Outbreaks are more common in people with HIV or other immune problems.
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HOW IS LEUKOPLAKIA DIAGNOSED?
- Leukoplakia which is non scrapable is usually diagnosed with an oral examination.
- If a patch looks suspicious, your healthcare provider will do a biopsy. To do a biopsy, they remove a small piece of tissue from one or more of your spots.
- They then send that tissue sample to a pathologist for diagnosis to check for precancerous or cancerous cells.
TREATMENT OPTIONS:
- Most patches improve on their own and don’t require any treatment. It’s important to avoid any triggers that may have caused your leukoplakia, such as tobacco use.
- If a biopsy comes back positive for oral cancer, the patch must be removed This can help prevent cancer cells from spreading.
- Patches can be removed by using laser therapy, a scalpel, or a freezing procedure.
- Hairy leukoplakia is not likely to result in mouth cancer and usually does not require removal.
- Your healthcare provider might prescribe antiviral medications to help stop the patches from growing.
- Topical ointments containing retinoic acid can also be used to reduce patch size.
PREVENTION:
Many cases of leukoplakia can be prevented with lifestyle changes:
LONG-TERM OUTLOOK FOR LEUKOPLAKIA?
However, if your patch is particularly painful or looks suspicious, your dentist may order tests to rule out:
- ORAL CANCER
- HIV
- AIDS
- A history of leukoplakia can increase your risk for oral cancer, so let your doctor know if you’ve noticed irregular patches in your mouth. Many of the risk factors for leukoplakia are also risk factors for oral cancer. Oral cancer can form alongside leukoplakia.
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About the Author
This article has been contributed by the Department of Oral Pathology & Microbiology, Yenepoya Dental College under the Yenepoya (Deemed to be University) established in the year 1992, with its robust alumni of 3000 Under graduates and 67 Post graduates students and research scholars has many accolades and achievements to its credit. It strives to provide state of art Oral diagnostics and Molecular Pathology while excelling in research activities and instilling a holistic approach in dental education among students.
Department contributes its expertise in fostering inter-disciplinary collaboration and providing exemplary education and scientific research.